Located between S.R. 78 and S.R. 70 on Hwy 721, West of Lake Okeechobee on the Brighton Seminole Indian Reservation.
From the West coast (Port Charlotte, Punta Gorda, Arcadia areas): Take Highway 70 East, cross over Highway 27 and continue approximately 15 miles to the flashing yellow light at Highway 721. Turn right (South), and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the East coast (Palm Beach, Stuart, Port St. Lucie areas): Take Highway 70 or HWY 714 to 710 West into Okeechobee (Approximately 45 miles). Continue on Highway 70 for approximately 18 miles to the flashing yellow light at Highway 721. Turn left (South) and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the North (Lake Wales, Frostproof, Arcadia, Sebring areas): Take Highway 27 South to Highway 70. Turn left or East on Highway 70. Continue approximately 15 miles to the flashing light at Highway 721. Turn right (South), and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the Treasure and Space Coast (Melbourne, Sebastian, Vero Beach areas): Take Highway 441 South into Okeechobee. Then turn right and take Highway 70 West approximately 18 miles to the flashing yellow light at Highway 721. Turn left and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the South: From Moore Haven, Clewiston and South Bay: Take Highway 27 North to Highway 78, then turn right and take Highway 78 East to Highway 721. Turn left (North) and continue 9 miles to the casino on your left. You may also follow the signs to the Seminole Indian Reservation.
From Fort Myers, Lehigh Acres and LaBelle: Take Highway 29 North to Highway 27. Turn right (South) to Highway 78. Turn right (South) on Highway 27 for a short distance. Turn left (east) and take Highway 78 to Highway 721. Turn left and continue 9 miles to the casino on your left. You may also follow the signs to the Seminole Indian Reservation.

Port St Lucie Fl Zillow

Located between S.R. 78 and S.R. 70 on Hwy 721, West of Lake Okeechobee on the Brighton Seminole Indian Reservation.
From the West coast (Port Charlotte, Punta Gorda, Arcadia areas): Take Highway 70 East, cross over Highway 27 and continue approximately 15 miles to the flashing yellow light at Highway 721. Turn right (South), and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the East coast (Palm Beach, Stuart, Port St. Lucie areas): Take Highway 70 or HWY 714 to 710 West into Okeechobee (Approximately 45 miles). Continue on Highway 70 for approximately 18 miles to the flashing yellow light at Highway 721. Turn left (South) and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the North (Lake Wales, Frostproof, Arcadia, Sebring areas): Take Highway 27 South to Highway 70. Turn left or East on Highway 70. Continue approximately 15 miles to the flashing light at Highway 721. Turn right (South), and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the Treasure and Space Coast (Melbourne, Sebastian, Vero Beach areas): Take Highway 441 South into Okeechobee. Then turn right and take Highway 70 West approximately 18 miles to the flashing yellow light at Highway 721. Turn left and continue 9 miles to the casino on your right. You may also follow the signs to the Seminole Indian Reservation.
From the South: From Moore Haven, Clewiston and South Bay: Take Highway 27 North to Highway 78, then turn right and take Highway 78 East to Highway 721. Turn left (North) and continue 9 miles to the casino on your left. You may also follow the signs to the Seminole Indian Reservation.
From Fort Myers, Lehigh Acres and LaBelle: Take Highway 29 North to Highway 27. Turn right (South) to Highway 78. Turn right (South) on Highway 27 for a short distance. Turn left (east) and take Highway 78 to Highway 721. Turn left and continue 9 miles to the casino on your left. You may also follow the signs to the Seminole Indian Reservation.

Port St. Lucie Florida Location Map

Casinos near Port St. Play Real Casino Experience - #1 Trusted USA Online Casino. 7177 S US Highway 1, Port St Lucie, FL (772) 343-7580. Casinos in Port Saint Lucie on YP.com. See reviews, photos, directions, phone numbers and more for the best Casinos in Port Saint Lucie, FL.